BioinformaticsbioRxivPreprint
SpaTRACE: Spatiotemporal recurrent auto-encoder for reconstructing signaling and regulatory networks from spatiotemporal transcriptomics data
Hongliang Zhou, Hao Chen, Zoe Rudnick…·Jose Lugo-Martinez
SpaTRACE jointly infers gene regulatory networks and cell-cell signaling from spatial transcriptomics data, outperforming existing methods in synthetic benchmarks and revealing novel interactions in development and regeneration.