Transcription drives DNA replication initiation and termination in human cells
Yu-Hung Chen, Sarah Keegan, Malik Kahli, Peter Tonzi, David Fenyö, Tony T. Huang, Duncan J. Smith
This study shows that DNA replication initiation and termination in human cells are coupled with transcription, with initiation near transcription start sites and termination at polyadenylation sites.
bioRxiv · May 16, 2018 · PreprintMolecular Biology