Decoding the Valence of Developmental Social Behavior: Dopamine Governs Social Motivation Deficits in Autism
Xinfeng Chen, Xianming Tao, Zhenchao Zhong, Yuanqing Zhang, Yixuan Li, Ye Ouyang, Zhaoyi Ding, Min An, Miao Wang, Ying Li
This study identifies NAc dopamine as a dynamic encoder of social valence and shows that modulating dopaminergic circuits can rescue social deficits in ASD models.
bioRxiv · Nov 12, 2025 · PreprintNeuroscience