nELAVL phosphorylation by CDKL5 regulates RNA metabolism and condensates communication to promote experience-dependent maturation of the visual cortex
Shiyang Yuan, Yao Zhu, Zhongyu Zheng, Hei Matthew Yip, Maggie See Wing Chan, Zhongjie Zhang, Yue Chai, Kyle R. Jenks, Katya Tsimring, Greggory R. Heller, José C. Zepeda, Marco Celotto, Hung Kwok Hung, Yangyang Duan, Shun‐Fat Lau, , Jacque Pak Kan Ip
This study identifies CDKL5-mediated phosphorylation of nELAVL as critical for regulating RNA metabolism and condensate communication, essential for visual cortex maturation.
bioRxiv · May 14, 2026 · PreprintNeuroscience