VAMP5 is a novel target for selective inhibition of gliomas with high NDRG4 expression via downregulating PLK1 and beyond
Yinghao Zhang, Yi‐Sheng Liu, Wanhong Zhang, Haoran Wang, Jin-Hai Wang, Yufang Sui
The paper identifies VAMP5 as a therapeutic target for gliomas with high NDRG4 expression, showing it downregulates PLK1 and other genes, with NDRG4 as a predictor of treatment sensitivity.
bioRxiv · May 12, 2025 · PreprintCancer Biology