Highly-accurate long-read sequencing improves variant detection and assembly of a human genome
Aaron M. Wenger, Paul S. Peluso, William J. Rowell, Pi-Chuan Chang, Richard J. Hall, Gregory T. Concepcion, Jana Ebler, Arkarachai Fungtammasan, Alexey Kolesnikov, Nathan D. Olson, Armin Töpfer, Michael Alonge, Medhat Mahmoud, Yufeng Qian, Chen-Shan Chin, , Michael W. Hunkapiller
This paper develops a long-read sequencing protocol to improve variant detection and genome assembly in a human genome, achieving high accuracy and contiguity.
Nature Biotechnology · Aug 12, 2019Peer-reviewedGenomics