Paul S. Peluso

The paper presents a phased whole genome assembly for Atlantic bluefin tuna using PacBio HiFi and Omni-C scaffolding, enabling improved phylogenomic and evolutionary studies.

The paper quantifies methylation inheritance in clonally propagated grapevines using phased genomes and multi-omics data, showing remarkable stability of epigenetic marks despite clonal variability.

This study examines antero-posterior patterning in brittle stars to understand axial homologies in echinoderms and their evolution.

The paper investigates molecular patterning in sea stars to determine if their body plan retains similarities with deuterostomes, finding no ectodermal territory expressing bilaterian trunk genetic programs.

A gapless 3.055 billion bp human genome from HiFi and ultra-long nanopore reads resolves all centromeric arrays and acrocentric p-arms, adding 182 Mbp of new sequence.

Trio-binned PacBio HiFi reads plus a 3.6 M-variant recombination map give phase-resolved assemblies of octoploid strawberry 'Royal Royce' and FaRR1, a 786.5 Mb haploid reference with 28 pseudomolecules.

FALCON-Phase uses long-read sequencing and Hi-C data to create phased diploid genome assemblies, achieving high accuracy in non-human species but lower accuracy in humans.

The paper presents a phased diploid assembly of the Cascade hop genome, revealing patterns of selection and haplotype variation, and identifies a homolog of CBDAS.

The paper provides highly accurate long-read HiFi sequencing datasets for five complex genomes to evaluate and develop bioinformatic tools.

This study compares HiFi and CLR long-read sequencing for human genome assembly, finding HiFi provides better continuity and accuracy in complex regions but not centromeres or segmental duplications.

This paper develops a long-read sequencing protocol to improve variant detection and genome assembly in a human genome, achieving high accuracy and contiguity.

The paper presents an improved Aedes aegypti genome assembly, AaegL5, which enhances biological understanding and vector control efforts by resolving key genomic features and identifying new targets for intervention.

The paper improves the maize reference genome using single molecule technologies, resulting in longer contigs and better annotation of repetitive elements and genes.

The paper improves the Atlantic cod genome assembly using long-read sequencing and multiple assembly programs, revealing a high density of tandem repeats and heterozygous variation.