A probiotic bacterium modulates antitumor γδ T-cell responses in lung cancer
Yoshihiko Goto, Garry M. Dolton, Hannah L. Thomas, Théo Morin, Yuka Tajima, Kosuke Imamura, Shinya Sakata, Kentaro Oka, Atsushi Hayashi, Motomichi Takahashi, Takamasa Ueno, Takuro Sakagami, Yusuke Tomita, Andrew Kelvin Sewell, Chihiro Motozono
This study shows that the probiotic CBM588 enhances antitumor γδ T-cell responses in lung cancer patients undergoing checkpoint blockade therapy.
bioRxiv · Jul 16, 2025 · PreprintImmunology