An absolute quantification atlas of small non-coding RNAs across diverse mammalian tissues and cell lines
Wen Xiao, Yuli Zheng, Hongdao Zhang, Beiying Xu, Ruiwen Zhang, Ligang Wu
The paper introduces 4NBoost, a sncRNA-seq protocol with spike-ins to improve quantification, and establishes a reference atlas revealing biases in miRNA and piRNA abundance across tissues and cell lines.
Nature Communications · Feb 3, 2026Peer-reviewedGenomics