SLC38A2 provides proline to fulfil unique synthetic demands arising during osteoblast differentiation and bone formation.
Leyao Shen, Yilin Yu, Yunji Zhou, Shondra M. Pruett-Miller, Guo-Fang Zhang, Courtney M. Karner
The paper identifies SLC38A2 as essential for proline supply during osteoblast differentiation and bone formation, showing its role in proline-rich protein synthesis.
eLife · Mar 9, 2022Peer-reviewedDevelopmental Biology