The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy
Yurika Ito, Mari Yamagata, Takuya Yamamoto, Katsuya Hirasaka, Takeshi Nikawa, Takahiko Sato
This study shows that loss of Mfn2 reduces MAM and activates Notch signaling in muscle atrophy, and DAPT treatment improves mitochondrial function and regeneration.
eLife · Dec 15, 2023Peer-reviewedDevelopmental Biology