Yuriy Mishchenko

Variability in cellular gene expression profiles and homeostatic regulation

The paper argues that variability in gene and protein expression in genetically and environmentally identical cells results from homeostatic regulation mechanisms.

Consistent estimation of complete neuronal connectivity in large neuronal populations using sparse "shotgun" neuronal activity sampling

The paper analyzes the shotgun sampling approach for estimating neuronal connectivity in large populations, finding it can infer complete connectivity matrices under general conditions but requires significant data when neuron numbers are small.

Application of the radial distribution function for quantitative analysis of neuropil microstructure in stratum radiatum of CA1 region in hippocampus.

This study uses radial distribution functions to analyze micrometer-scale organization of neuropil in rat hippocampal CA1, finding disordered axonal and dendritic arrangements with deviations in glia and dendritic spines.

Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics

The paper evaluates the cost and performance of different connectomics strategies for whole mouse brain mapping, identifying potential cost reductions with emerging technologies.