Author

Yusuke Sekiguchi

St. Jude Children's Research Hospital

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Amanda NourseiD· 1 shared Marcin W. WłodarskiiD· 1 shared Michael L. OldhamiD· 1 shared Ravi KalathuriD· 1 shared Sushree Sangita SahooiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Amanda NourseORCID

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1 paper

Recent·Most cited

Cryo-EM structures of SAMD9L reveal the arrangement and coordination of multi-domains

Yusuke Sekiguchi, Sushree Sangita Sahoo, Michael L. Oldham, Amanda Nourse, Marcin W. Włodarski, Ravi Kalathur

This study determines the cryo-EM structures of hSAMD9L and an N-terminal-truncated mutant, revealing their multi-domain architecture, dimerization, and nucleotide binding properties.

bioRxiv · Feb 2, 2026 · PreprintBiochemistry