Novel single-domain AA12 pyrroloquinoline quinone-dependent oxidoreductases directly and co-operatively drive lytic polysaccharide monooxygenase activity with AA8 module
Yuxing Sun, Congcong Yuan, Liangkun Long, Shaojun Ding
This study identifies single-domain AA12 oxidoreductases and free AA8 modules as direct and cooperative electron donors to lytic polysaccharide monooxygenase (LPMO) in cellulolytic fungi.
bioRxiv · Sep 2, 2025 · PreprintBiochemistry