MNC-RED a Chemically Defined Method to Produce Enucleated Red Blood Cells from Adult Peripheral Blood Mononuclear Cells
S. E. Zhang, E. E. Olivier, Z. E. Yan, S. E. Suzuka, K. E. Roberts, K. E. Wang, E. E. Bouhassira
The paper develops a cost-effective protocol, MNC-RED, to produce enucleated red blood cells from peripheral blood mononuclear cells using a chemically defined medium, R6, with reduced transferrin and iron chelator.
bioRxiv · Apr 25, 2019 · PreprintBioengineering