Author

Z. Jagani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

F. Rago· 2 shared G. Elliott· 2 shared H.-e. C. Bhang· 2 shared A. Bric· 1 shared A. Kauffmann· 1 shared A. Li· 1 shared A. Vattay· 1 shared C. D. Adair· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

F. Rago

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Author profile →

2 papers

Recent·Most cited

Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia

F. Rago, L. U. Rodrigues, M. Bonney, K. Sprouffske, E. Kurth, G. Elliott, J. Ambrose, P. Aspesi, J. Oborski, J. T. Chen, E. R. McDonald, F. A. Mapa, D. A. Ruddy, A. Kauffmann, T. Abrams, , Z. Jagani

This study shows that dual BRG1/BRM ATPase inhibitors are effective against AML cell lines, revealing broad SWI/SNF dependencies and suggesting therapeutic potential.

bioRxiv · Apr 23, 2021Cancer Biology

In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling

Z. Jagani, G. Chenail, K. Xiang, G. Bushold, H.-E. C. Bhang, A. Li, G. Elliott, J. Zhu, A. Vattay, T. Gilbert, A. Bric, R. Kikkawa, V. Dubost, R. Terranova, J. Cantwell, , Haas

This study validates novel BRM/BRG1 ATPase inhibitors as chemical probes for SWI/SNF chromatin remodeling and shows their therapeutic potential in BRG1-mut lung cancers.

bioRxiv · Oct 22, 2019 · PreprintCancer Biology