Accelerated Protein Biomarker Discovery from FFPE tissue samples using Single-shot, Short Gradient Microflow SWATH MS
R. Sun, C. Hunter, C. Chen, G. Weigang, N. Morrice, S. Liang, Y. c. Hui, Q. Zhang, X. Cai, X. Yu, L. Chen, S. Dai, Z. Luan, R. Aebersold, Y. Zhu, T. Guo
This paper introduces an accelerated SWATH MS method for protein biomarker discovery in FFPE tissues, showing reduced instrument time and batch effects while maintaining good protein quantification and clinical separation.
bioRxiv · Oct 7, 2019Cancer Biology