Tissue Folding by Mechanical Compaction of the Mesenchyme
A. J. Hughes, H. Miyazaki, M. C. Coyle, J. Zhang, M. T. Laurie, D. Chu, Z. Vavrusova, R. A. Schneider, O. D. Klein, Z. J. Gartner
This study shows mechanical compaction of mesenchyme drives tissue folding in vitro through ECM strain and collagen alignment, without genetic engineering.
bioRxiv · Jul 15, 2017Bioengineering