Structural insights into human ABCC4 mediated transport of platelet agonist and inhibitor
Y. Chen, L. Wang, W.-T. Hou, Z.-H. Zha, K. Xu, C.-Z. Zhou, Q. Li, Y. Chen
This study determines the structures of human ABCC4 in apo and complexed forms, revealing its role in exporting platelet agonists and inhibitors, and identifying a pocket for drug design.
bioRxiv · Dec 25, 2022 · PreprintBiochemistry