Synthetic BiologybioRxivPreprint
Verification of genetic engineering in yeasts with nanopore whole genome sequencing
Joseph H. Collins, Kevin W. Keating, Trent R. Jones…·Eric M. Young
The paper introduces Prymetime, a workflow for accurate whole genome sequencing of engineered yeasts, showing it can assemble and annotate synthetic parts and detect unintended modifications.
DOI 10.1101/2020.05.05.079368