Astrocytic contribution to auditory hypersensitivity in a mouse model of fragile X syndrome
Lara Bergdolt, Alexandria Anding, Ola Alshaqi, Zahra Arbabi, Michael Douchey, Ember Eldridge, Katherine Hoffman, Ashley Reid, Kiran Sapkota, Ragunathan Padmashri, Daniel T. Monaghan, Olga D. Taraschenko, Anna Dunaevksy
This study shows that reducing FMRP in astrocytes contributes to auditory hypersensitivity and spontaneous seizures in a mouse model of FXS, but not tactile hypersensitivity.
bioRxiv · Feb 14, 2025 · PreprintNeuroscience