Ragunathan Padmashri

The paper studies calcium signaling in human-specific interlaminar astrocytes in a chimeric mouse model of Fragile X Syndrome, finding hyperexcitable signaling and increased dendritic spine turnover.

This study shows that reducing FMRP in astrocytes contributes to auditory hypersensitivity and spontaneous seizures in a mouse model of FXS, but not tactile hypersensitivity.

The paper shows that brief ischemia causes transient calpain-dependent disruption of axon initial segments in hippocampal granule cells, which can be prevented by blocking Na+/Ca2+ exchanger activity.

This study uses human pluripotent stem cell-derived cerebral organoids to show that oligodendrogenesis in the human brain has both ventral and dorsal origins, with dorsal cells dominating in fused organoids.