Ectopic expression of the germline transcription factor LSL-1 contributes to developmental delay following failed maternal epigenetic reprogramming
Benjamin Nguyen, Zaynab Massenburg, Joshua Labus, Sundas Hassan Johnson, Sarah D. Blancher, Miyah Jones, Brandon S. Carpenter
The paper shows that LSL-1, a germline transcription factor, contributes to developmental delay when maternal epigenetic reprogramming fails, by promoting ectopic gene expression in somatic tissues.
bioRxiv · Sep 3, 2026 · PreprintDevelopmental Biology