Brandon S. Carpenter

The paper shows that LSL-1, a germline transcription factor, contributes to developmental delay when maternal epigenetic reprogramming fails, by promoting ectopic gene expression in somatic tissues.

The paper shows that DREAM and MEC NuRD complexes reinforce SPR-5/MET-2 maternal reprogramming to prevent germline gene expression in somatic tissues and developmental delay in C. elegans.

This study identifies KIF17 as a dual regulator of Hedgehog signaling in cerebellar development, with opposing roles in Purkinje cells and granule neuron progenitors.

The paper shows that CoREST facilitates maternal reprogramming of histone methylation by SPR-5/LSD1 in C. elegans and mice.

The paper shows that in C. elegans, the balance between histone methylation systems MES-4 and SPR-5; MET-2 is essential for distinguishing germline from soma and preventing developmental delay.

The paper shows that H3K9me2 protects lifespan in C. elegans by counteracting the transgenerational effects of germline transcription.

This paper describes a portable short course designed to engage underrepresented undergraduate students in developmental biology, showing improved understanding and awareness of scientific careers.