Adaptive resampling for improved machine learning in imbalanced single-cell datasets
Zeinab Navidi, Akshaya Thoutam, Madeline Hughes, Srivatsan Raghavan, Peter S. Winter, Lorin A. Crawford, Ava P. Amini
This paper introduces an adaptive resampling method to improve machine learning performance on imbalanced single-cell datasets, showing better results in gene expression reconstruction, cell type classification, and perturbation response prediction.
bioRxiv · Nov 4, 2025 · PreprintBioinformatics