Esteban Alberto Miglietta

A scalable approach to resolving variants of uncertain significance

The paper develops a scalable workflow to reclassify variants of uncertain significance using experimental and predictive evidence, resolving 75% of VUS in 40 genes.

O-mannosylation and protein maturation check-points represent therapeutic opportunities in BRAF fusion protein oncogenesis

The paper identifies O-mannosylation and protein maturation as therapeutic targets in BRAF fusion oncogenesis by showing their necessity for fusion-induced transformation.

Enhanced auxin signaling hub triggers root hair growth at moderate low temperature in Arabidopsis thaliana

MorphoDiff: Cellular Morphology Painting with Diffusion Models

MorphoDiff predicts high-resolution cell morphology changes under different interventions using diffusion models and perturbation embeddings.

A Postdoctoral Training Program in Bioimage Analysis

This paper describes a postdoctoral training program in bioimage analysis, highlighting its components, outcomes, and implications for training experts in professional skills.