Ectopic hepatocyte transplantation cures the pig model of tyrosinemia
Clara T. Nicolas, Robert A. Kaiser, Raymond Hickey, Kari L. Allen, Zeji Du, Caitlin J. VanLith, Rebekah M. Guthman, Bruce P. Amiot, Lukkana Suksanpaisan, Bing Han, Maria Giovanna Francipane, Amin Cheikhi, Huailei Jiang, Aditya Bansal, Mukesh K. Pandey, , Joseph B. Lillegard
The paper demonstrates that transplanting corrected hepatocytes into mesenteric lymph nodes cures a pig model of tyrosinemia by repopulating the diseased liver and restoring liver function.
Molecular Therapy — Methods & Clinical Development · Jul 9, 2020Peer-reviewedMolecular Biology