Aditya Vijay Bhagwate

This study identifies ARID5A as a PERK-dependent effector of ER stress that protects against steatohepatitis in mice.

This study shows that intestinal stem cells from IBD patients retain epigenetic memory of inflammation, leading to heightened responses to future injury but also increased risk of relapse.

This study identifies epigenomic and transcriptional changes in intestinal organoids from obese individuals with hyperabsorption, linking them to increased nutrient uptake.

The paper identifies miR-29 and ATG9A as regulators of mitophagy and discovers EOPD-linked variants in ATG9A.

The paper demonstrates that transplanting corrected hepatocytes into mesenteric lymph nodes cures a pig model of tyrosinemia by repopulating the diseased liver and restoring liver function.

This study evaluates RNA extraction and capture methods for RNA-seq from FFPE tissues, finding high correlation in gene expression profiles with sufficient RNA quality and demonstrating improved fusion detection with TruSeq RNA Access.

The paper evaluates nine FFPE DNA extraction methods for NGS, finding average WES coverage of ~20-30X and 99% genotype concordance with targeted panels.