Single-protein diffusion in micrometer-size vesicles is governed by viscosity, surface charge, and membrane interactions
Jelmer Coenradij, Dmitrii Linnik, Kristine Postmus, Zeynap Sensan, Matilde Accorsi, Christiaan Michiel Punter, Rumiana Dimova, Bert Poolman
This study quantifies how viscosity, surface charge, and membrane interactions affect single-protein diffusion in GUVs, revealing membrane-proximal interactions and long-range charge effects.
bioRxiv · Oct 22, 2026 · PreprintBiophysics