Bert Poolman

This study quantifies how viscosity, surface charge, and membrane interactions affect single-protein diffusion in GUVs, revealing membrane-proximal interactions and long-range charge effects.

The paper shows that accessible Gibbs energy at metabolic activation limits long-term cell growth by constraining metabolic reorganization and ATP production.

The paper shows that protein agglomerates in E. coli regulate cytoplasmic rheology, with diffusion inversely correlating with amino acid metabolism protein abundance.

The paper shows that the substrate-binding domains of OpuA transiently interact in an ionic strength-dependent manner, supporting a cooperative transport mechanism.

The paper constructs a synthetic metabolic network in vitro to maintain ATP levels and physicochemical homeostasis, demonstrating energy conservation and cell volume regulation in a cell-like system.

The paper shows a mutation in CcpA improves fitness in Lactococcus lactis by reprogramming transporters, revealing membrane occupancy as a constraint.