Author

Zhaowen Cheng

Hangzhou Institute of Medicine, Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Research Focus:software / tool· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:large language model· 1 Assay:multiome· 1 Organism:multiple species· 1

Frequent Co-Authors

Mei LangiD· 3 shared Mingxuan CheniD· 3 shared Xiagu Zhu· 3 shared Xingyu FangiD· 3 shared Zhen WangiD· 3 shared Junwei Zhang· 2 shared Kin Yip TamiD· 2 shared Xiaolin LiiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBioinformatics

Mei LangORCID

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3 papers

Recent·Most cited

EukaUTR: a foundation model unifying functional modelling and design of eukaryotic 3' UTRs

Mei Lang, Xingyu Fang, Mingxuan Chen, Zhen Wang, Zhaowen Cheng, Xiagu Zhu, Kin Yip Tam, Junwei Zhang, Xiaolin Li

EukaUTR is a foundation model for eukaryotic 3' UTRs that predicts function and generates new sequences with regulatory properties.

bioRxiv · Sep 10, 2026 · PreprintBioinformatics

CodonMamba: a foundation model for programmable mRNA coding sequence design

Mei Lang, Xingyu Fang, Zhen Wang, Mingxuan Chen, Zhaowen Cheng, Xiagu Zhu, Kin Yip Tam, Junwei Zhang, Xiaolin Li

CodonMamba is a foundation model for mRNA coding sequence design that achieves state-of-the-art performance and enables programmable codon optimization through inference-time steering.

bioRxiv · Aug 24, 2026 · PreprintBioinformatics

UTRGen: A unified framework for full-spectrum design of mRNA 5' UTRs

Zhen Wang, Mingxuan Chen, Xiagu Zhu, Xingyu Fang, Zhaowen Cheng, Mei Lang, Junwei Zhang, Junjie Huang, Xiaolin Li

UTRGen is a unified framework for designing mRNA 5' UTRs that integrates sequence generation, prediction, and function-guided optimization, achieving state-of-the-art performance across multiple tasks.

bioRxiv · Jun 27, 2026 · PreprintBioinformatics