Kin Yip Tam

EukaUTR is a foundation model for eukaryotic 3' UTRs that predicts function and generates new sequences with regulatory properties.

CodonMamba is a foundation model for mRNA coding sequence design that achieves state-of-the-art performance and enables programmable codon optimization through inference-time steering.

This study identifies protein damage response (PDR) as a key mechanism in cancer drug resistance, showing that targeting PDR components can enhance drug efficacy in resistant cells.