PET-Microplastics Trigger Endothelial Glycocalyx Loss via ER Stress and ROS Unleashing IL-1β-Driven SMC Switching and Early Aortic Structural Impairment
Weixue Huo, Jin Qu, Sen Wang, Mengwei He, Zhaoxiang Zeng, Deping Kong, Lushun Yuan, Rui Feng
This study shows PET-MPs cause endothelial glycocalyx loss through ER stress and ROS, leading to IL-1β-driven smooth muscle cell switching and aortic structural damage.
Journal of Nanobiotechnology · Mar 11, 2026Peer-reviewedPharmacology & Toxicology