Author

Zheng Guo

Beijing Institute of Technology

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Chuan FuiD· 1 shared Feng Wang· 1 shared Jialong Xiong· 1 shared Ruoyi Lyu· 1 shared Shutong Li· 1 shared Tong Cai· 1 shared Wei Xu· 1 shared Xinqi GongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Chuan FuORCID

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1 paper

Recent·Most cited

CatIF-RL: Activity-Oriented Enzyme Sequence Design by Steered Inverse Protein Folding

Yanheng Li, Jialong Xiong, Yuxin Zhang, Tong Cai, Chuan Fu, Shutong Li, Wei Xu, Ruoyi Lyu, Zhaoyang Chen, Zheng Guo, Xinqi Gong, Feng Wang

CatIF-RL designs enzyme variants with enhanced catalytic activity by steering an inverse folding model using predicted kcat as an optimization objective.

Journal of Chemical Information and Modeling · Jul 17, 2026Peer-reviewedBioinformatics