Author

Shutong Li

University of Southern California

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chao QiniD· 2 shared Pinghui FengiD· 2 shared Shu FengiD· 2 shared Yongzhen LiuiD· 2 shared Alexandra Shambayate· 1 shared Ali Can SavasiD· 1 shared Canhua HuangiD· 1 shared Casey CheniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersMicrobiology

Chao QinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CatIF-RL: Activity-Oriented Enzyme Sequence Design by Steered Inverse Protein Folding

Yanheng Li, Jialong Xiong, Yuxin Zhang, Tong Cai, Chuan Fu, Shutong Li, Wei Xu, Ruoyi Lyu, Zhaoyang Chen, Zheng Guo, Xinqi Gong, Feng Wang

CatIF-RL designs enzyme variants with enhanced catalytic activity by steering an inverse folding model using predicted kcat as an optimization objective.

Journal of Chemical Information and Modeling · Jul 17, 2026Peer-reviewedBioinformatics

Bacteria-herpesvirus interaction reveals a proviral role of ISGylation in promoting herpesvirus capsid assembly

Shutong Li, Shu Feng, Yongzhen Liu, Chao Qin, Jianglin Zhang, Takeru Saito, Xinchi Xie, Wen Fu, Rui Wang, Yue Zheng, Zhenfeng Shu, Wayne Wei Yeh, Sean Sasaki, Natalia O. Tjokro, Lin Chen, , Pinghui Feng

This study shows that ISGylation, induced by bacterial co-infection, promotes herpesvirus capsid assembly and replication by modifying viral proteins.

bioRxiv · Jan 20, 2026 · PreprintMicrobiology

The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection

Shu Feng, Na Xie, Yongzhen Liu, Chao Qin, Ali Can Savas, Tingyu Wang, Shutong Li, Youliang Rao, Alexandra Shambayate, Tsui‐Fen Chou, Charles Brenner, Canhua Huang, Pinghui Feng

This study identifies NAMPT's phosphoribosyl-hydrolase activity as a mechanism to restrict HSV-1 infection by de-phosphoribosylating viral structural proteins.

Nature Metabolism · Nov 21, 2024Peer-reviewedMolecular Biology