Author

Zhenghua Wang

Fudan University

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Biology Disciplines

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Biophysics· 1

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Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:protein structure prediction· 1 Approach:variational autoencoder· 1

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Fengyu Yang· 1 shared Haibin LingiD· 1 shared Jing YuaniD· 1 shared Quanquan GuiD· 1 shared S. C. CheniD· 1 shared Shahar Z. KovalskyiD· 1 shared Xiaoqing ZhengiD· 1 shared Yi ZhouiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Fengyu Yang

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1 paper

Recent·Most cited

A Generative Foundation Model for Cryo-EM Densities

Yilai Li, Jing Yuan, Yi Zhou, Zhenghua Wang, S. C. Chen, Fengyu Yang, Haibin Ling, Shahar Z. Kovalsky, Xiaoqing Zheng, Quanquan Gu

This paper introduces cryoFM, a generative foundation model for cryo-EM densities that improves reconstruction and refinement by combining data-driven priors with dataset-specific constraints.

bioRxiv · Dec 29, 2025 · PreprintBiophysics