Author

Zhenhong Huang

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Research Focus:polygenic risk· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Manuela CostantinoiD· 2 shared Andy Dahl· 1 shared Andy W. DahliD· 1 shared Iain MathiesoniD· 1 shared Renée FonsecaiD· 1 shared Sriram SankararamaniD· 1 shared Zhengtong LiuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersGenetics

Manuela CostantinoORCID

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2 papers

Recent·Most cited

Optimizing phenotype scale improves genetic analyses in large-scale biobanks

Zhenhong Huang, Manuela Costantino, Andy Dahl

SIQReg optimizes phenotype scales in genetic analyses, improving both additive and non-additive signal detection in large biobanks.

bioRxiv · May 7, 2026 · PreprintGenetics

Choice of phenotype scale is critical in biobank-based GxE tests

Manuela Costantino, Renée Fonseca, Zhengtong Liu, Zhenhong Huang, Sriram Sankararaman, Iain Mathieson, Andy W. Dahl

The paper shows that phenotype scale choice affects GxE signals in biobank data, with log scaling revealing meaningful effects and explaining a significant portion of PGSxSex interactions.

bioRxiv · Jan 21, 2026 · PreprintGenetics