Circadian regulation of hippocampal function is disrupted with chronic corticosteroid treatment
Matthew T. Birnie, Matthew D. B. Claydon, Oliver R Troy, Benjamin P. Flynn, Mitsuhiro Yoshimura, Yvonne M. Kershaw, Zidong Zhao, Rebecca C. R. Demski-Allen, Gareth R. I. Barker, Elizabeth Clea Warburton, Zuner Assis Bortolotto, Stafford Louis Lightman, Becky L. Conway-Campbell
This study shows chronic corticosteroid exposure disrupts circadian regulation of hippocampal function and synaptic plasticity in rats, leading to memory loss.
Proceedings of the National Academy of Sciences · Apr 6, 2023Peer-reviewedNeuroscience