Author
University of BristolORCID 0000-0002-8546-9646Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Matthew D. B. Claydon, Oliver R Troy, Matthew T. Birnie, Yvonne M. Kershaw, Gareth R. I. Barker, Elizabeth Clea Warburton, Zuner Assis Bortolotto, Stafford Louis Lightman, Becky L. Conway-Campbell
This study shows that chronic corticosteroid treatment disrupts synaptic structure and cognitive function in the perirhinal cortex.
bioRxiv · Jun 6, 2025 · PreprintNeuroscience
Isabella Marinelli, Jamie J. Walker, Udaya K. Seneviratne, Wendyl Jude D'Souza, Mark James Cook, Clare Anderson, Andrew P. Bagshaw, Stafford Louis Lightman, Wessel Woldman, John R. Terry
The paper uses a mathematical model to analyze EEG data from people with epilepsy and identifies cortisol levels and sleep stages as factors explaining daily variability in epileptiform discharges.
PLoS Computational Biology · Oct 5, 2023Peer-reviewedNeuroscience
Matthew T. Birnie, Matthew D. B. Claydon, Oliver R Troy, Benjamin P. Flynn, Mitsuhiro Yoshimura, Yvonne M. Kershaw, Zidong Zhao, Rebecca C. R. Demski-Allen, Gareth R. I. Barker, Elizabeth Clea Warburton, Zuner Assis Bortolotto, Stafford Louis Lightman, Becky L. Conway-Campbell
This study shows chronic corticosteroid exposure disrupts circadian regulation of hippocampal function and synaptic plasticity in rats, leading to memory loss.
Proceedings of the National Academy of Sciences · Apr 6, 2023Peer-reviewedNeuroscience
Philippe C. Habets, Konstantinos Kalafatakis, Oleh Dzyubachyk, Steven J.A. van der Werff, Arlin Keo, Jamini Thakrar, Ahmed Essam Mahfouz, Alberto M. Pereira, Georgina M. Russell, Stafford Louis Lightman, Onno Cornelis Meijer
The paper examines how loss of ultradian cortisol rhythm affects emotional processing in cortical brain regions by analyzing transcriptional and cell type profiles.
Neurobiology of Stress · Jan 1, 2023Peer-reviewedNeuroscience
Geffen Lass, Xiao Feng Li, Margaritis Voliotis, Ellen Wall, Ross de Burgh, Deyana Ivanova, Caitlin McIntyre, Xian‐Hua Lin, William Henry Colledge, Stafford Louis Lightman, Krasimira T. Tsaneva-Atanasova, Kevin T. O'Byrne
The paper investigates how kisspeptin neurons in the medial amygdala modulate GnRH pulse frequency through GABA and glutamate neurotransmission in female mice.
Journal of Neuroendocrinology · Oct 17, 2022Peer-reviewedNeuroscience
Eder Zavala, Margaritis Voliotis, Tanja Zerenner, Joël Tabak, Jamie J. Walker, Xiao Feng Li, John R. Terry, Stafford Louis Lightman, Kevin T. O’Byrne, Krasimira T. Tsaneva-Atanasova
This paper models the HPA and HPG axes as coupled oscillators to understand how stress perturbations affect fertility and hormone dynamics.
Frontiers in Physiology · Nov 17, 2020Peer-reviewedSystems Biology
Geffen Lass, Xiao Feng Li, Ross de Burgh, Wen He, Yanping Kang, Yeo Shel-Hwa, Lydia C. Sinnett‐Smith, William Henry Colledge, Matthew Grubb, Stafford Louis Lightman, Kevin O'Byrne
The paper shows that optogenetic stimulation of MePD kisspeptin neurons in female mice increases LH pulse frequency, suggesting their role in regulating the GnRH pulse generator.
Journal of Neuroendocrinology · Dec 24, 2019Peer-reviewedNeuroscience