Meiotic cohesion requires Sirt1 and preserving its activity in aging oocytes reduces missegregation
Zihan Meng, Nicholas G. Norwitz, Sharon E. Bickel
This study shows that Sirt1 maintains meiotic cohesion in Drosophila oocytes, and preserving its activity during aging reduces chromosome segregation errors.
EMBO Reports · Nov 10, 2025Peer-reviewedCell Biology