FAIMS-GPF XL-MS: crosslinking-mass spectrometry based on gas-phase fractionation
Hugo Gizardin-Fredon, Salvatore Terrosu, Simon Pichard, Zinédine Loukili, Dursun Nizam Korkut, Cathy Braun, Arnaud Poterszman, Clément Charenton, Sarah Cianférani
The paper introduces FAIMS-GPF XL-MS, a method for detecting protein-protein interactions using gas-phase fractionation, achieving high sensitivity and coverage without in-solution fractionation.
Nature Communications · Jul 23, 2026Peer-reviewedSystems Biology