Extracellular signalling regulates gastrin transcription through site-specific phosphorylation and nuclear redistribution of Menin
Uloma B. Elvis‐Offiah, Ziyu Wen, Xianxin Hua, Juanita L. Merchant
This study shows extracellular signaling regulates gastrin transcription by phosphorylating Menin at Ser487, causing its nuclear redistribution and loss of tumor-suppressor function.
bioRxiv · Apr 10, 2026 · PreprintCancer Biology