Disorder in coiled-coils orchestrate chromatin organization and define a new permeability barrier at the nuclear pore basket
Zoé Narat, Stefany Figueroa, Axelle Donjon, Christine M. Doucet, Nouhaila Laabas, Charlène Boumendil
The paper identifies disordered regions in the coiled-coil domain of TPR, showing they form condensates and create a permeability barrier at the nuclear pore basket.
bioRxiv · Jul 18, 2025 · PreprintCell Biology