Dual Role of Microglial TREM2 in Neuronal Degeneration and Regeneration After Axotomy
Tana S. Pottorf, Elizabeth L. Lane, Zoë Haley-Johnson, Desirée N. Ukmar, Veronica Amores-Sanchez, Patricia M. Correa-Torres, Francisco J. Álvarez
This study investigates how TREM2 in microglia influences neuronal degeneration and regeneration after axotomy, finding TREM2 promotes removal of degenerating motoneurons and supports regeneration of others.
Journal of Neuroscience · Apr 10, 2026Peer-reviewedNeuroscience