Evaluation of the genotoxic potential of dietary metabolites to support the renewal of an active substance under European Commission Regulation (EC) 1107/2009 -- fludioxonil case study
Zofi A. McKenzie, Anne-Sophie Parant, K. Bridgwood, Ewan D. Booth
This paper evaluates the genotoxic potential of three dietary metabolites of fludioxonil using a tiered approach involving (Q)SAR, read across, and various in vitro and in vivo genotoxicity assays, concluding they pose no genotoxic concern.
Food and Chemical Toxicology · Nov 28, 2025Peer-reviewedPharmacology & Toxicology