FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility
Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
This study shows that FBXO24 deletion in mice leads to abnormal RNP granule accumulation in sperm flagella, causing infertility due to impaired flagellar structure and sperm motility.
eLife · Jan 24, 2024Peer-reviewedDevelopmental Biology