Yichen Wang

The paper reports mutation rates and mutational signatures across 53 normal human cell types, revealing variation in mutation accumulation and identifying known and unknown mutational processes.

The paper identifies mutational signatures in normal kidney cells from multiple countries, revealing exposure to exogenous mutagens including aristolochic acids and unknown agents prevalent in Japan.

This study identifies somatic and germline mutational signatures across 661 species, revealing greater diversity than in human samples, likely due to environmental or biological factors.

This study uses whole-genome sequencing to analyze somatic mutations in normal gastric epithelium, revealing mutation rates, clonal dynamics, and associations with cancer risk factors.

NetID identifies lineage-specific gene regulatory networks from scRNA-seq data by improving GRN inference through metacell-based analysis and avoids spurious correlations.