Author

Molly Perchlik

University of WashingtonORCID 0000-0001-5158-9079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Josh T. CuperusiD· 2 shared Alexander SasseiD· 1 shared Christine QueitschiD· 1 shared Kerry L. BubbiD· 1 shared Sara MostafaviiD· 1 shared Stanley FieldsiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

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6 top collaborators · 9 mutual co-author links

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2 shared papersGenomics

Josh T. CuperusORCID

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2 papers

Recent·Most cited

GenomicsFrontiers in Epigenetics and EpigenomicsPeer-reviewedOct 27, 2026

Unpacking Chromatin Accessibility with Fiber-seq

Kerry L. Bubb, Molly Perchlik, Josh T. Cuperus, Christine Queitsch

This paper introduces Fiber-seq, a method for detecting chromatin accessibility on individual DNA fibers, and provides guidelines for its proper use and analysis.

DOI 10.3389/freae.2026.1968465

ATAC-seqexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJun 21, 2023

Impact of random 50-base sequences inserted into an intron on splicing in Saccharomyces cerevisiae

Molly Perchlik, Alexander Sasse, Sara Mostafavi…·Josh T. Cuperus

The paper inserts random 50-base sequences into yeast introns and finds that most reduce splicing efficiency, likely due to RNA secondary structures, but existing models poorly predict these effects.

DOI 10.1101/2023.06.21.545966

yeastDNA methylation

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