Author

Dario Meluzzi

University of California San DiegoORCID 0000-0001-5185-264XUnclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

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Approach:deep learning· 1 Approach:statistical model· 1

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Anushka Saha· 1 shared Dhruva KatrekariD· 1 shared Nathan PalmeriD· 1 shared Prashant MaliiD· 1 shared Yichen XiangiD· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperSynthetic Biology

Anushka Saha

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1 paper

Recent·Most cited

Synthetic BiologyeLifePeer-reviewedJan 19, 2022

Comprehensive interrogation of the ADAR2 deaminase domain for engineering enhanced RNA base-editing activity, functionality and specificity

Dhruva Katrekar, Nathan Palmer, Yichen Xiang…·Prashant Mali

This study engineers ADAR2 deaminase variants to enhance RNA editing activity, specificity, and functionality through deep mutational scans, domain-wide mutagenesis, and split deaminase design.

51 citations

deep learningstatistical model

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