Genetic & Genomic MedicinemedRxivPreprint
Common and rare variants in SLCO1B1 are associated with statin intolerance
Margherita Bigossi, Cyrielle Maroteau, Adem Y. Dawed…·Moneeza Kalhan Siddiqui
This study shows that considering both loss-of-function and gain-of-function variants in SLCO1B1 improves the prediction of statin intolerance compared to using only the Val174Ala variant.
DOI 10.1101/2022.08.09.22278584